Field safety studies, which examined the vaccine when used in the first, second and third trimesters of pregnancy, showed no systemic or local reactions to vaccination

Leptospirosis Vaccine Approved for Mare Pregnancy

Elevate Antibody Titer Levels

The equine leptospirosis vaccine against L. pomona receives additional approval for use through the duration of a mare’s pregnancy. Equine leptospirosis is an infectious bacterial disease caused by spirochetes.

Field safety studies examined LEPTO EQ INNOVATOR in the first, second, and third trimesters. The vaccine showed no systemic or local reactions, according to Zoetis.

“Leptospires can cause late-term abortion in mares,” said Jacquelin Boggs, DVM, MS, ACVIM, senior veterinarian, Equine Technical Services at Zoetis. “The expanded label claim allows the equine breeding community the flexibility to use LEPTO EQ INNOVATOR to fit their breeding program’s needs and help elevate antibody titer levels when most needed.”

A study shows 13% of bacterial abortions are from L. pomona. Aborting mares can reportedly shed leptospires in their urine for up to three months and transmit Leptospira to exposed animals.

L. pomona can colonize in the kidneys, be shed in the urine and cause horses to become septicemic. The bacteria circulates in the blood and causes uveitis, or moon blindness, as well as abortions and kidney failure.

Some horses aborting due to leptospiral infection develop uveitis several weeks to months later.

Additionally, the aborted fetus is a source of exposure to other horses in the vicinity.

Prior to launching LEPTO EQ INNOVATOR, Zoetis conducted safety and efficacy trials. Vaccinated horses with L. pomona experienced no urinary shedding. Additional studies showed 99.8% of vaccinated horses were reaction-free with no adverse events.

LEPTO EQ INNOVATOR helps prevent leptospiremia caused by Leptospira interrogans serovar Pomona (L. pomona). It could, but has not been demonstrated to, help reduce the potential risk of equine recurrent uveitis (ERU) infections, abortions or acute renal failure caused by L. pomona. No vaccine is labeled with those indications the company notes.

Previously unvaccinated healthy mares should receive two doses of LEPTO EQ INNOVATOR approximately three to four weeks apart. Annual re-vaccination is recommended.

Speak with your veterinarian for more information.